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T Cell-Derived IL-10 Determines Leishmaniasis Disease Outcome and Is Suppressed by a Dendritic Cell Based Vaccine

In the murine model of Leishmania major infection, resistance or susceptibility to the parasite has been associated with the development of a Th1 or Th2 type of immune response. Recently, however, the immunosuppressive effects of IL-10 have been ascribed a crucial role in the development of the diff...

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Detalles Bibliográficos
Autores principales: Schwarz, Tobias, Remer, Katharina A., Nahrendorf, Wiebke, Masic, Anita, Siewe, Lisa, Müller, Werner, Roers, Axel, Moll, Heidrun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694851/
https://www.ncbi.nlm.nih.gov/pubmed/23825956
http://dx.doi.org/10.1371/journal.ppat.1003476