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T Cell-Derived IL-10 Determines Leishmaniasis Disease Outcome and Is Suppressed by a Dendritic Cell Based Vaccine
In the murine model of Leishmania major infection, resistance or susceptibility to the parasite has been associated with the development of a Th1 or Th2 type of immune response. Recently, however, the immunosuppressive effects of IL-10 have been ascribed a crucial role in the development of the diff...
Autores principales: | Schwarz, Tobias, Remer, Katharina A., Nahrendorf, Wiebke, Masic, Anita, Siewe, Lisa, Müller, Werner, Roers, Axel, Moll, Heidrun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694851/ https://www.ncbi.nlm.nih.gov/pubmed/23825956 http://dx.doi.org/10.1371/journal.ppat.1003476 |
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