DC8 and DC13 var Genes Associated with Severe Malaria Bind Avidly to Diverse Endothelial Cells

During blood stage infection, Plasmodium falciparum infected erythrocytes (IE) bind to host blood vessels. This virulence determinant enables parasites to evade spleen-dependent killing mechanisms, but paradoxically in some cases may reduce parasite fitness by killing the host. Adhesion of infected...

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Detalles Bibliográficos
Autores principales: Avril, Marion, Brazier, Andrew J., Melcher, Martin, Sampath, Sowmya, Smith, Joseph D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694856/
https://www.ncbi.nlm.nih.gov/pubmed/23825944
http://dx.doi.org/10.1371/journal.ppat.1003430

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694856/
https://www.ncbi.nlm.nih.gov/pubmed/23825944
http://dx.doi.org/10.1371/journal.ppat.1003430

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