Cargando…

Tetanus Toxin Hc Fragment Induces the Formation of Ceramide Platforms and Protects Neuronal Cells against Oxidative Stress

Tetanus toxin (TeTx) is the protein, synthesized by the anaerobic bacteria Clostridium tetani, which causes tetanus disease. TeTx gains entry into target cells by means of its interaction with lipid rafts, which are membrane domains enriched in sphingomyelin and cholesterol. However, the exact mecha...

Descripción completa

Detalles Bibliográficos
Autores principales: Cubí, Roger, Candalija, Ana, Ortega, Arturo, Gil, Carles, Aguilera, José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694913/
https://www.ncbi.nlm.nih.gov/pubmed/23826362
http://dx.doi.org/10.1371/journal.pone.0068055