Role of mTOR, Bad, and Survivin in RasGAP Fragment N-Mediated Cell Protection

Partial cleavage of p120 RasGAP by caspase-3 in stressed cells generates an N-terminal fragment, called fragment N, which activates an anti-apoptotic Akt-dependent survival response. Akt regulates several effectors but which of these mediate fragment N-dependent cell protection has not been defined...

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Detalles Bibliográficos
Autores principales: Peltzer, Nieves, Vanli, Güliz, Yang, Jiang-Yan, Widmann, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694949/
https://www.ncbi.nlm.nih.gov/pubmed/23826368
http://dx.doi.org/10.1371/journal.pone.0068123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694949/
https://www.ncbi.nlm.nih.gov/pubmed/23826368
http://dx.doi.org/10.1371/journal.pone.0068123

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