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Role of mTOR, Bad, and Survivin in RasGAP Fragment N-Mediated Cell Protection
Partial cleavage of p120 RasGAP by caspase-3 in stressed cells generates an N-terminal fragment, called fragment N, which activates an anti-apoptotic Akt-dependent survival response. Akt regulates several effectors but which of these mediate fragment N-dependent cell protection has not been defined...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694949/ https://www.ncbi.nlm.nih.gov/pubmed/23826368 http://dx.doi.org/10.1371/journal.pone.0068123 |