Global Identification of EVI1 Target Genes in Acute Myeloid Leukemia

The ecotropic virus integration site 1 (EVI1) transcription factor is associated with human myeloid malignancy of poor prognosis and is overexpressed in 8–10% of adult AML and strikingly up to 27% of pediatric MLL-rearranged leukemias. For the first time, we report comprehensive genomewide EVI1 bind...

Descripción completa

Detalles Bibliográficos
Autores principales: Glass, Carolyn, Wuertzer, Charles, Cui, Xiaohui, Bi, Yingtao, Davuluri, Ramana, Xiao, Ying-Yi, Wilson, Michael, Owens, Kristina, Zhang, Yi, Perkins, Archibald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694976/
https://www.ncbi.nlm.nih.gov/pubmed/23826213
http://dx.doi.org/10.1371/journal.pone.0067134

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694976/
https://www.ncbi.nlm.nih.gov/pubmed/23826213
http://dx.doi.org/10.1371/journal.pone.0067134

Ejemplares similares