TGF-β-Neutralizing Antibody 1D11 Enhances Cytarabine-Induced Apoptosis in AML Cells in the Bone Marrow Microenvironment

Hypoxia and interactions with bone marrow (BM) stromal cells have emerged as essential components of the leukemic BM microenvironment in promoting leukemia cell survival and chemoresistance. High levels of transforming growth factor beta 1 (TGFβ1) produced by BM stromal cells in the BM niche regulat...

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Detalles Bibliográficos
Autores principales: Tabe, Yoko, Shi, Yue Xi, Zeng, Zhihong, Jin, Linhua, Shikami, Masato, Hatanaka, Yasuhito, Miida, Takashi, Hsu, Frank J., Andreeff, Michael, Konopleva, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695026/
https://www.ncbi.nlm.nih.gov/pubmed/23826077
http://dx.doi.org/10.1371/journal.pone.0062785

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695026/
https://www.ncbi.nlm.nih.gov/pubmed/23826077
http://dx.doi.org/10.1371/journal.pone.0062785

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