Frizzled6 deficiency disrupts the differentiation process of nail development

Nails protect the soft tissue of the tips of digits. The molecular mechanism of nail (and claw) development is largely unknown, but we have recently identified a Wnt receptor gene, Frizzled6 (Fzd6) that is mutated in a human autosomal-recessive nail dysplasia. To investigate the action of Fzd6 in cl...

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Detalles Bibliográficos
Autores principales: Cui, Chang-Yi, Klar, Joakim, Georgii-Heming, Patrik, Fröjmark, Anne-Sophie, Baig, Shahid M., Schlessinger, David, Dahl’, Niklas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695035/
https://www.ncbi.nlm.nih.gov/pubmed/23439395
http://dx.doi.org/10.1038/jid.2013.84

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695035/
https://www.ncbi.nlm.nih.gov/pubmed/23439395
http://dx.doi.org/10.1038/jid.2013.84

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