DNA hypomethylation within specific transposable element families associates with tissue-specific enhancer landscape

Transposable element (TE) derived sequences comprise half of our genome and DNA methylome, and are presumed densely methylated and inactive. Examination of the genome-wide DNA methylation status within 928 TE subfamilies in human embryonic and adult tissues revealed unexpected tissue-specific and su...

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Detalles Bibliográficos
Autores principales: Xie, Mingchao, Hong, Chibo, Zhang, Bo, Lowdon, Rebecca, Xing, Xiaoyun, Li, Daofeng, Zhou, Xin, Lee, Hyung Joo, Maire, Cecile L., Ligon, Keith L., Gascard, Philippe, Sigaroudinia, Mahvash, Tlsty, Thea D., Kadlecek, Theresa, Weiss, Arthur, O’Geen, Henriette, Farnham, Peggy J., Madden, Pamela A.F., Mungall, Andrew J., Tam, Angela, Kamoh, Baljit, Cho, Stephanie, Moore, Richard, Hirst, Martin, Marra, Marco A., Costello, Joseph F., Wang, Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695047/
https://www.ncbi.nlm.nih.gov/pubmed/23708189
http://dx.doi.org/10.1038/ng.2649

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695047/
https://www.ncbi.nlm.nih.gov/pubmed/23708189
http://dx.doi.org/10.1038/ng.2649

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