Astrocyte-Specific Overexpression of Insulin-Like Growth Factor-1 Protects Hippocampal Neurons and Reduces Behavioral Deficits following Traumatic Brain Injury in Mice

Traumatic brain injury (TBI) survivors often suffer from long-lasting cognitive impairment that stems from hippocampal injury. Systemic administration of insulin-like growth factor-1 (IGF-1), a polypeptide growth factor known to play vital roles in neuronal survival, has been shown to attenuate post...

Descripción completa

Detalles Bibliográficos
Autores principales: Madathil, Sindhu K., Carlson, Shaun W., Brelsfoard, Jennifer M., Ye, Ping, D’Ercole, A. Joseph, Saatman, Kathryn E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695083/
https://www.ncbi.nlm.nih.gov/pubmed/23826235
http://dx.doi.org/10.1371/journal.pone.0067204

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695083/
https://www.ncbi.nlm.nih.gov/pubmed/23826235
http://dx.doi.org/10.1371/journal.pone.0067204

Ejemplares similares