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Circulating Methylated XAF1 DNA Indicates Poor Prognosis for Gastric Cancer

BACKGROUND: Methylated DNA in fluids may be a suitable biomarker for cancer patients. XAF1 has been shown to be frequently down-regulated in human gastric cancer (GC). Here, we investigated if XAF1 methylation in GC could be a useful biomarker. METHODS: Real-time RT-PCR was used to detect XAF1 mRNA...

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Detalles Bibliográficos
Autores principales: Ling, Zhi-Qiang, Lv, Ping, Lu, Xiao-Xiao, Yu, Jiang-Liu, Han, Jing, Ying, Li-Sha, Zhu, Xin, Zhu, Wang-Yu, Fang, Xian-Hua, Wang, Shi, Wu, Yi-Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695092/
https://www.ncbi.nlm.nih.gov/pubmed/23826230
http://dx.doi.org/10.1371/journal.pone.0067195