Dopamine Release Suppression Dependent on an Increase of Intracellular Ca(2+) Contributed to Rotenone-induced Neurotoxicity in PC12 Cells

Rotenone is an inhibitor of mitochondrial complex I that produces a model of Parkinson’s disease (PD), in which neurons undergo dopamine release dysfunction and other features. In neurons, exocytosis is one of the processes associated with dopamine release and is dependent on Ca(2+) dynamic changes...

Descripción completa

Detalles Bibliográficos
Autores principales: Sai, Yan, Chen, Junfeng, Ye, Feng, Zhao, Yuanpeng, Zou, Zhongmin, Cao, Jia, Dong, Zhaojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society of Toxicologic Pathology 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695337/
https://www.ncbi.nlm.nih.gov/pubmed/23914057
http://dx.doi.org/10.1293/tox.26.149

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695337/
https://www.ncbi.nlm.nih.gov/pubmed/23914057
http://dx.doi.org/10.1293/tox.26.149

Ejemplares similares