Thioacetamide-induced Hepatocellular Necrosis Is Attenuated in Diet-induced Obese Mice

To assess modification of thioacetamide-induced hepatotoxicity in mice fed a high-fat diet, male C57BL/6J mice were fed a normal rodent diet or a high-fat diet for 8 weeks and then treated once intraperitoneally with thioacetamide at 50 mg/kg body weight. At 24 and 48 hours after administration, mas...

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Detalles Bibliográficos
Autores principales: Shirai, Makoto, Arakawa, Shingo, Miida, Hiroaki, Matsuyama, Takuya, Kinoshita, Junzo, Makino, Toshihiko, Kai, Kiyonori, Teranishi, Munehiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society of Toxicologic Pathology 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695339/
https://www.ncbi.nlm.nih.gov/pubmed/23914059
http://dx.doi.org/10.1293/tox.26.175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695339/
https://www.ncbi.nlm.nih.gov/pubmed/23914059
http://dx.doi.org/10.1293/tox.26.175

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