Influence of genome-scale RNA structure disruption on the replication of murine norovirus—similar replication kinetics in cell culture but attenuation of viral fitness in vivo

Mechanisms by which certain RNA viruses, such as hepatitis C virus, establish persistent infections and cause chronic disease are of fundamental importance in viral pathogenesis. Mammalian positive-stranded RNA viruses establishing persistence typically possess genome-scale ordered RNA secondary str...

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Detalles Bibliográficos
Autores principales: McFadden, Nora, Arias, Armando, Dry, Inga, Bailey, Dalan, Witteveldt, Jeroen, Evans, David J., Goodfellow, Ian, Simmonds, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695492/
https://www.ncbi.nlm.nih.gov/pubmed/23630317
http://dx.doi.org/10.1093/nar/gkt334

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695492/
https://www.ncbi.nlm.nih.gov/pubmed/23630317
http://dx.doi.org/10.1093/nar/gkt334

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