APOBEC3G cytosine deamination hotspots are defined by both sequence context and single-stranded DNA secondary structure

Apolipoprotein B mRNA-editing, enzyme-catalytic, polypeptide-like 3G (i.e., APOBEC3G or A3G) is an evolutionarily conserved cytosine deaminase that potently restricts human immunodeficiency virus type 1 (HIV-1), retrotransposons and other viruses. A3G has a nucleotide target site specificity for cyt...

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Detalles Bibliográficos
Autores principales: Holtz, Colleen M., Sadler, Holly A., Mansky, Louis M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695494/
https://www.ncbi.nlm.nih.gov/pubmed/23620282
http://dx.doi.org/10.1093/nar/gkt246

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695494/
https://www.ncbi.nlm.nih.gov/pubmed/23620282
http://dx.doi.org/10.1093/nar/gkt246

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