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APOBEC3G cytosine deamination hotspots are defined by both sequence context and single-stranded DNA secondary structure
Apolipoprotein B mRNA-editing, enzyme-catalytic, polypeptide-like 3G (i.e., APOBEC3G or A3G) is an evolutionarily conserved cytosine deaminase that potently restricts human immunodeficiency virus type 1 (HIV-1), retrotransposons and other viruses. A3G has a nucleotide target site specificity for cyt...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695494/ https://www.ncbi.nlm.nih.gov/pubmed/23620282 http://dx.doi.org/10.1093/nar/gkt246 |