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The tRNA-modifying function of MnmE is controlled by post-hydrolysis steps of its GTPase cycle
MnmE is a homodimeric multi-domain GTPase involved in tRNA modification. This protein differs from Ras-like GTPases in its low affinity for guanine nucleotides and mechanism of activation, which occurs by a cis, nucleotide- and potassium-dependent dimerization of its G-domains. Moreover, MnmE requir...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695501/ https://www.ncbi.nlm.nih.gov/pubmed/23630314 http://dx.doi.org/10.1093/nar/gkt320 |