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Challenges in homology search: HMMER3 and convergent evolution of coiled-coil regions
Detection of protein homology via sequence similarity has important applications in biology, from protein structure and function prediction to reconstruction of phylogenies. Although current methods for aligning protein sequences are powerful, challenges remain, including problems with homologous ov...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695513/ https://www.ncbi.nlm.nih.gov/pubmed/23598997 http://dx.doi.org/10.1093/nar/gkt263 |