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Synthesis of (18)O-labeled RNA for application to kinetic studies and imaging

Radioisotopes and fluorescent compounds are frequently used for RNA labeling but are unsuitable for clinical studies of RNA drugs because of the risk from radiation exposure or the nonequivalence arising from covalently attached fluorophores. Here, we report a practical phosphoramidite solid-phase s...

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Detalles Bibliográficos
Autores principales: Hamasaki, Tomohiro, Matsumoto, Takahiro, Sakamoto, Naoya, Shimahara, Akiko, Kato, Shiori, Yoshitake, Ayumi, Utsunomiya, Ayumi, Yurimoto, Hisayoshi, Gabazza, Esteban C., Ohgi, Tadaaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695515/
https://www.ncbi.nlm.nih.gov/pubmed/23632164
http://dx.doi.org/10.1093/nar/gkt344