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The SMC1-SMC3 cohesin heterodimer structures DNA through supercoiling-dependent loop formation

Cohesin plays a critical role in sister chromatid cohesion, double-stranded DNA break repair and regulation of gene expression. However, the mechanism of how cohesin directly interacts with DNA remains unclear. We report single-molecule experiments analyzing the interaction of the budding yeast cohe...

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Detalles Bibliográficos
Autores principales: Sun, Mingxuan, Nishino, Tatsuya, Marko, John F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695518/
https://www.ncbi.nlm.nih.gov/pubmed/23620281
http://dx.doi.org/10.1093/nar/gkt303