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The SMC1-SMC3 cohesin heterodimer structures DNA through supercoiling-dependent loop formation
Cohesin plays a critical role in sister chromatid cohesion, double-stranded DNA break repair and regulation of gene expression. However, the mechanism of how cohesin directly interacts with DNA remains unclear. We report single-molecule experiments analyzing the interaction of the budding yeast cohe...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695518/ https://www.ncbi.nlm.nih.gov/pubmed/23620281 http://dx.doi.org/10.1093/nar/gkt303 |