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Imprinted silencing is extended over broad chromosomal domains in mouse extra-embryonic lineages
Gene silencing in imprinted gene clusters is established by an epigenetic initiator that is often a long non-coding (lnc) RNA. The clustered organization of known imprinted genes indicates that the initiator extends imprinted silencing over broader chromosomal domains in extra-embryonic lineages com...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695569/ https://www.ncbi.nlm.nih.gov/pubmed/23478214 http://dx.doi.org/10.1016/j.ceb.2013.02.012 |