Abnormal body iron distribution and erythropoiesis in a novel mouse model with inducible gain of iron regulatory protein (IRP)-1 function

Disorders of iron metabolism account for some of the most common human diseases. Cellular iron homeostasis is maintained by iron regulatory proteins (IRP)-1 and 2 through their binding to cis-regulatory iron-responsive elements (IREs) in target mRNAs. Mouse models with IRP deficiency have yielded va...

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Detalles Bibliográficos
Autores principales: Casarrubea, D., Viatte, L., Hallas, T., Vasanthakumar, A., Eisenstein, R. S., Schümann, K., Hentze, M. W., Galy, B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695688/
https://www.ncbi.nlm.nih.gov/pubmed/23455710
http://dx.doi.org/10.1007/s00109-013-1008-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695688/
https://www.ncbi.nlm.nih.gov/pubmed/23455710
http://dx.doi.org/10.1007/s00109-013-1008-2

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