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Adeno-associated virus-mediated expression of growth-associated protein-43 aggravates retinal ganglion cell death in experimental chronic glaucomatous injury

PURPOSE: To examine whether adeno-associated virus (AAV) vector-mediated overexpression of growth-associated protein-43 (GAP-43) has protective or deleterious effects on retinal ganglion cell (RGC) survival in laser-induced chronic intraocular pressure (IOP) elevation injury. METHODS: Adult Fischer...

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Detalles Bibliográficos
Autores principales: Huang, Chukai, Cen, Ling-Ping, Liu, Lifang, Leaver, Simone G., Harvey, Alan R., Cui, Qi, Pang, Chi Pui, Zhang, Mingzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695761/
https://www.ncbi.nlm.nih.gov/pubmed/23825922