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GWAS on your notebook: fast semi-parallel linear and logistic regression for genome-wide association studies

BACKGROUND: Genome-wide association studies have become very popular in identifying genetic contributions to phenotypes. Millions of SNPs are being tested for their association with diseases and traits using linear or logistic regression models. This conceptually simple strategy encounters the follo...

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Detalles Bibliográficos
Autores principales: Sikorska, Karolina, Lesaffre, Emmanuel, Groenen, Patrick FJ, Eilers, Paul HC
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695771/
https://www.ncbi.nlm.nih.gov/pubmed/23711206
http://dx.doi.org/10.1186/1471-2105-14-166