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Live-virus exposure of vaccine-protected macaques alters the anti-HIV-1 antibody repertoire in the absence of viremia

BACKGROUND: We addressed the question whether live-virus challenges could alter vaccine-induced antibody (Ab) responses in vaccinated rhesus macaques (RMs) that completely resisted repeated exposures to R5-tropic simian-human immunodeficiency viruses encoding heterologous HIV clade C envelopes (SHIV...

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Detalles Bibliográficos
Autores principales: Bachler, Barbara C, Humbert, Michael, Lakhashe, Samir K, Rasmussen, Robert A, Ruprecht, Ruth M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695773/
https://www.ncbi.nlm.nih.gov/pubmed/23800339
http://dx.doi.org/10.1186/1742-4690-10-63