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BCL11A overexpression predicts survival and relapse in non-small cell lung cancer and is modulated by microRNA-30a and gene amplification

BACKGROUND: Aberrant activation of the proto-oncogene B-cell lymphoma/leukemia 11A (BCL11A) has been implicated in the pathogenesis of leukemia and lymphoma. However, the clinical significance of BCL11A in non-small cell lung cancer (NSCLC) remains unknown. RESULTS: We examined BCL11A expression at...

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Detalles Bibliográficos
Autores principales: Jiang, Ben-yuan, Zhang, Xu-chao, Su, Jian, Meng, Wei, Yang, Xue-ning, Yang, Jin-ji, Zhou, Qing, Chen, Zhi-yong, Chen, Zhi-hong, Xie, Zhi, Chen, Shi-liang, Wu, Yi-long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695801/
https://www.ncbi.nlm.nih.gov/pubmed/23758992
http://dx.doi.org/10.1186/1476-4598-12-61