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Statistical ensemble analysis for simulating extrinsic noise-driven response in NF-κB signaling networks
BACKGROUND: Gene expression profiles and protein dynamics in single cells have a large cell-to-cell variability due to intracellular noise. Intracellular fluctuations originate from two sources: intrinsic noise due to the probabilistic nature of biochemical reactions and extrinsic noise due to rando...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695840/ https://www.ncbi.nlm.nih.gov/pubmed/23742268 http://dx.doi.org/10.1186/1752-0509-7-45 |