Cargando…

Statistical ensemble analysis for simulating extrinsic noise-driven response in NF-κB signaling networks

BACKGROUND: Gene expression profiles and protein dynamics in single cells have a large cell-to-cell variability due to intracellular noise. Intracellular fluctuations originate from two sources: intrinsic noise due to the probabilistic nature of biochemical reactions and extrinsic noise due to rando...

Descripción completa

Detalles Bibliográficos
Autores principales: Joo, Jaewook, Plimpton, Steven J, Faulon, Jean-Loup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695840/
https://www.ncbi.nlm.nih.gov/pubmed/23742268
http://dx.doi.org/10.1186/1752-0509-7-45