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Prion Peptide Uptake in Microglial Cells – The Effect of Naturally Occurring Autoantibodies against Prion Protein

In prion disease, a profound microglial activation that precedes neurodegeneration has been observed in the CNS. It is still not fully elucidated whether microglial activation has beneficial effects in terms of prion clearance or whether microglial cells have a mainly detrimental function through th...

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Detalles Bibliográficos
Autores principales: Roettger, Yvonne, Zerr, Inga, Dodel, Richard, Bach, Jan-Philipp
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695867/
https://www.ncbi.nlm.nih.gov/pubmed/23840767
http://dx.doi.org/10.1371/journal.pone.0067743