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Generation of Reactive Oxygen Species by Polyenylpyrroles Derivatives Causes DNA Damage Leading to G2/M Arrest and Apoptosis in Human Oral Squamous Cell Carcinoma Cells

Oral squamous cell carcinoma (OSCC) accounts for 5.8% of all malignancies in Taiwan and the incidence of OSCC is on the rise. OSCC is also a common malignancy worldwide and the five-year survival rate remains poor. Therefore, new and effective treatments are needed to control OSCC. In the present st...

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Detalles Bibliográficos
Autores principales: Hua, Kuo-Feng, Liao, Pei-Chun, Fang, Zhanxiong, Yang, Feng-Ling, Yang, Yu-Liang, Chen, Yi-Lin, Chiu, Yi-Chich, Liu, May-Lan, Lam, Yulin, Wu, Shih-Hsiung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695893/
https://www.ncbi.nlm.nih.gov/pubmed/23840748
http://dx.doi.org/10.1371/journal.pone.0067603