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Correlation of Gene Expression and Genome Mutation in Single B-Cells

High-throughput measurement of gene-expression and immune receptor repertoires have recently become powerful tools in the study of adaptive immune response. However, despite their now-widespread use, both tend to discard cell identity by treating cell populations in bulk, and therefore lose the corr...

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Detalles Bibliográficos
Autores principales: Weinstein, Joshua A., Zeng, Xun, Chien, Yueh-Hsiu, Quake, Stephen R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695916/
https://www.ncbi.nlm.nih.gov/pubmed/23840752
http://dx.doi.org/10.1371/journal.pone.0067624