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Comparison of Lentiviral and Sleeping Beauty Mediated αβ T Cell Receptor Gene Transfer

Transfer of tumour antigen-specific receptors to T cells requires efficient delivery and integration of transgenes, and currently most clinical studies are using gamma retroviral or lentiviral systems. Whilst important proof-of-principle data has been generated for both chimeric antigen receptors an...

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Detalles Bibliográficos
Autores principales: Field, Anne-Christine, Vink, Conrad, Gabriel, Richard, Al-Subki, Roua, Schmidt, Manfred, Goulden, Nicholas, Stauss, Hans, Thrasher, Adrian, Morris, Emma, Qasim, Waseem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695921/
https://www.ncbi.nlm.nih.gov/pubmed/23840834
http://dx.doi.org/10.1371/journal.pone.0068201