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ABCC1 Is Related to the Protection of the Distal Nephron against Hyperosmolality and High Sodium Environment: Possible Implications for Cancer Chemotherapy

AIMS: Glutathione (GSH) plays an important role in protecting cells against oxidative damage. ABCC1 protein transports GSH. Although this protein is largely studied in cancer, due to multidrug resistance phenotype, its role in the tubular cells of the kidney is unknown. The goal of this study was to...

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Detalles Bibliográficos
Autores principales: Fonseca, Leonardo M., Alvarez, Adriana B., Rodrigues, Rachel C., Santos, Diego H. F., Lopes, Anibal G., Capella, Marcia A. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695945/
https://www.ncbi.nlm.nih.gov/pubmed/23840808
http://dx.doi.org/10.1371/journal.pone.0068049