Anti-Inflammation of Spirocyclopiperazinium Salt Compound LXM-10 Targeting α7 nAChR and M4 mAChR and Inhibiting JAK2/STAT3 Pathway in Rats

The present study aims to investigate the therapeutic effects of LXM-10 by intragastric administration in both acute and chronic inflammatory models, and to explore the underlying molecular mechanisms. The results showed that LXM-10 produced significant anti-inflammatory effects on carrageenan induc...

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Detalles Bibliográficos
Autores principales: Zhang, Weiwei, Sun, Qi, Gao, Xiaoli, Jiang, Yimin, Li, Runtao, Ye, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695990/
https://www.ncbi.nlm.nih.gov/pubmed/23840548
http://dx.doi.org/10.1371/journal.pone.0066895

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695990/
https://www.ncbi.nlm.nih.gov/pubmed/23840548
http://dx.doi.org/10.1371/journal.pone.0066895

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