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A Genome-Wide siRNA Screen to Identify Host Factors Necessary for Growth of the Parasite Toxoplasma gondii

Toxoplasma gondii is an obligate intracellular parasite that is able to infect virtually any nucleated cell of all warm-blooded animals. The host cell factors important for parasite attachment, invasion, and replication are poorly understood. We screened a siRNA library targeting 18,200 individual h...

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Detalles Bibliográficos
Autores principales: Moser, Lindsey A., Pollard, Angela M., Knoll, Laura J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695992/
https://www.ncbi.nlm.nih.gov/pubmed/23840822
http://dx.doi.org/10.1371/journal.pone.0068129