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Cyclic AMP-Response Element Regulated Cell Cycle Arrests in Cancer Cells

Recently, we have demonstrated that trichosanthin (TCS), a promising agent for the treatment of cervical adenocarcinoma, inhibited HeLa cell proliferation through the PKC/MAPK/CREB signal pathway. Furthermore, TCS down-regulated Bcl-2 expression was abrogated by a decoy oligonucleotide (OGN) to the...

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Detalles Bibliográficos
Autores principales: Wang, Ping, Huang, Shuaishuai, Wang, Feng, Ren, Yu, Hehir, Michael, Wang, Xue, Cai, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3696002/
https://www.ncbi.nlm.nih.gov/pubmed/23840351
http://dx.doi.org/10.1371/journal.pone.0065661