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Interaction of Complement Factor H and Fibulin3 in Age-Related Macular Degeneration

Age-related macular degeneration (AMD) is a major cause of vision loss. It is associated with development of characteristic plaque-like deposits (soft drusen) in Bruch’s membrane basal to the retinal pigment epithelium (RPE). A sequence variant (Y402H) in short consensus repeat domain 7 (SCR7) of co...

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Detalles Bibliográficos
Autores principales: Wyatt, M. Keith, Tsai, Jen-Yue, Mishra, Sanghamitra, Campos, Maria, Jaworski, Cynthia, Fariss, Robert N., Bernstein, Steven L., Wistow, Graeme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3696004/
https://www.ncbi.nlm.nih.gov/pubmed/23840815
http://dx.doi.org/10.1371/journal.pone.0068088