Mitochondrial Bioenergetics of Metastatic Breast Cancer Cells in Response to Dynamic Changes in Oxygen Tension: Effects of HIF-1α

Solid tumors are characterized by regions of low oxygen tension (OT), which play a central role in tumor progression and resistance to therapy. Low OT affects mitochondrial function and for the cells to survive, mitochondria must functionally adapt to low OT to maintain the cellular bioenergetics. I...

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Detalles Bibliográficos
Autores principales: Diers, Anne R., Vayalil, Praveen K., Oliva, Claudia R., Griguer, Corinne E., Darley-Usmar, Victor, Hurst, Douglas R., Welch, Danny R., Landar, Aimee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3696014/
https://www.ncbi.nlm.nih.gov/pubmed/23840849
http://dx.doi.org/10.1371/journal.pone.0068348

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3696014/
https://www.ncbi.nlm.nih.gov/pubmed/23840849
http://dx.doi.org/10.1371/journal.pone.0068348

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