Tetraspanin CD9 Promotes the Invasive Phenotype of Human Fibrosarcoma Cells via Upregulation of Matrix Metalloproteinase-9

Tumor cell metastasis, a process which increases the morbidity and mortality of cancer patients, is highly dependent upon matrix metalloproteinase (MMP) production. Small molecule inhibitors of MMPs have proven unsuccessful at reducing tumor cell invasion in vivo. Therefore, finding an alternative a...

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Detalles Bibliográficos
Autores principales: Herr, Michael J., Kotha, Jayaprakash, Hagedorn, Nikolaus, Smith, Blake, Jennings, Lisa K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3696041/
https://www.ncbi.nlm.nih.gov/pubmed/23840773
http://dx.doi.org/10.1371/journal.pone.0067766

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3696041/
https://www.ncbi.nlm.nih.gov/pubmed/23840773
http://dx.doi.org/10.1371/journal.pone.0067766

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