Cargando…

SPCA2 Regulates Orai1 Trafficking and Store Independent Ca(2+) Entry in a Model of Lactation

An unconventional interaction between SPCA2, an isoform of the Golgi secretory pathway Ca(2+)-ATPase, and the Ca(2+) influx channel Orai1, has previously been shown to contribute to elevated Ca(2+) influx in breast cancer derived cells. In order to investigate the physiological role of this interact...

Descripción completa

Detalles Bibliográficos
Autores principales: Cross, Brandie M., Hack, Anniesha, Reinhardt, Timothy A., Rao, Rajini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3696057/
https://www.ncbi.nlm.nih.gov/pubmed/23840669
http://dx.doi.org/10.1371/journal.pone.0067348