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Mutation Analysis of IDH1 in Paired Gliomas Revealed IDH1 Mutation Was Not Associated with Malignant Progression but Predicted Longer Survival

Recurrence and progression to higher grade lesions are characteristic behaviorsof gliomas. Though IDH1 mutation frequently occurs and is considered as an early event in gliomagenesis, little is known about its role in the recurrence and progression of gliomas. We therefore analysed IDH1 and IDH2 sta...

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Detalles Bibliográficos
Autores principales: Yao, Yu, Chan, Aden Ka-Yin, Qin, Zhi Yong, Chen, Ling Chao, Zhang, Xin, Pang, Jesse Chung-Sean, Li, Hiu Ming, Wang, Yin, Mao, Ying, NG, Ho-Keung, Zhou, Liang Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3696098/
https://www.ncbi.nlm.nih.gov/pubmed/23840696
http://dx.doi.org/10.1371/journal.pone.0067421