A basic residue in the proximal C-terminus is necessary for efficient activation of the M-channel subunit Kv7.2 by PI(4,5)P(2)

All Kv7 potassium channels require membrane phosphatidylinositol-4,5-bisphosphate (PI(4,5)P(2)) for their normal function and hence can be physiologically regulated by neurotransmitters and hormones that stimulate phosphoinositide hydrolysis. Recent mutational analysis indicates that a cluster of ba...

Descripción completa

Detalles Bibliográficos
Autores principales: Telezhkin, Vsevolod, Thomas, Alison M., Harmer, Stephen C., Tinker, Andrew, Brown, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2013
Materias:
Ion Channels, Receptors and Transporters
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3696465/
https://www.ncbi.nlm.nih.gov/pubmed/23291709
http://dx.doi.org/10.1007/s00424-012-1199-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3696465/
https://www.ncbi.nlm.nih.gov/pubmed/23291709
http://dx.doi.org/10.1007/s00424-012-1199-3

Ejemplares similares