Efficient Biodistribution and Gene Silencing in the Lung epithelium via Intravenous Liposomal Delivery of siRNA

RNA interference (RNAi) may provide a therapeutic solution to many pulmonary epithelium diseases. However, the main barrier to the clinical use of RNAi remains the lack of efficient delivery vectors. Research has mainly concentrated on the intranasal route of delivery of short interfering RNA (siRNA...

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Detalles Bibliográficos
Autores principales: McCaskill, Jana, Singhania, Richa, Burgess, Melinda, Allavena, Rachel, Wu, Sherry, Blumenthal, Antje, McMillan, Nigel AJ
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3696903/
https://www.ncbi.nlm.nih.gov/pubmed/23736774
http://dx.doi.org/10.1038/mtna.2013.22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3696903/
https://www.ncbi.nlm.nih.gov/pubmed/23736774
http://dx.doi.org/10.1038/mtna.2013.22

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