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An Approach for Identifiability of Population Pharmacokinetic–Pharmacodynamic Models
Mathematical models are routinely used in clinical pharmacology to study the pharmacokinetic and pharmacodynamic properties of a drug in the body. Identifiability of these models is an important requirement for the success of these clinical studies. Identifiability is classified into two types, stru...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3697038/ https://www.ncbi.nlm.nih.gov/pubmed/23887745 http://dx.doi.org/10.1038/psp.2013.25 |