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An Approach for Identifiability of Population Pharmacokinetic–Pharmacodynamic Models

Mathematical models are routinely used in clinical pharmacology to study the pharmacokinetic and pharmacodynamic properties of a drug in the body. Identifiability of these models is an important requirement for the success of these clinical studies. Identifiability is classified into two types, stru...

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Detalles Bibliográficos
Autores principales: Shivva, V, Korell, J, Tucker, I G, Duffull, S B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3697038/
https://www.ncbi.nlm.nih.gov/pubmed/23887745
http://dx.doi.org/10.1038/psp.2013.25