Antitumor Molecular Mechanism of Chlorogenic Acid on Inducting Genes GSK-3β and APC and Inhibiting Gene β-Catenin

Objective. Inhibiting gene β-catenin and inducting genes GSK-3β and APC, promoting the tumor cell apoptosis in Wnt pathway, by chlorogenic acid were discussed (CGA). Method. The different genes were scanned by the 4∗44K mouse microarray chips. The effect of the three genes was confirmed by RT-PCR te...

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Detalles Bibliográficos
Autores principales: Xu, Ruoshi, Kang, Qiumei, Ren, Jie, Li, Zukun, Xu, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3697783/
https://www.ncbi.nlm.nih.gov/pubmed/23844319
http://dx.doi.org/10.1155/2013/951319

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3697783/
https://www.ncbi.nlm.nih.gov/pubmed/23844319
http://dx.doi.org/10.1155/2013/951319

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