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Candida albicans CUG Mistranslation Is a Mechanism To Create Cell Surface Variation

In the human fungal pathogen Candida albicans, the CUG codon is translated 97% of the time as serine and 3% of the time as leucine, which potentially originates an array of proteins resulting from the translation of a single gene. Genes encoding cell surface proteins are enriched in CUG codons; thus...

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Detalles Bibliográficos
Autores principales: Miranda, Isabel, Silva-Dias, Ana, Rocha, Rita, Teixeira-Santos, Rita, Coelho, Carolina, Gonçalves, Teresa, Santos, Manuel A. S., Pina-Vaz, Cidália, Solis, Norma V., Filler, Scott G., Rodrigues, Acácio G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3697807/
https://www.ncbi.nlm.nih.gov/pubmed/23800396
http://dx.doi.org/10.1128/mBio.00285-13