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Is the Nickel-Dependent Urease Complex of Cryptococcus the Pathogen’s Achilles’ Heel?
The nitrogen-scavenging enzyme urease has been coopted in a variety of pathogenic organisms as a virulence factor, most notoriously to neutralize stomach acid and establish infection by the gastric pathogen Helicobacter pylori. The opportunistic fungal pathogen Cryptococcus neoformans also utilizes...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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American Society of Microbiology
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3697809/ https://www.ncbi.nlm.nih.gov/pubmed/23800398 http://dx.doi.org/10.1128/mBio.00408-13 |