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Reconstruction of viral population structure from next-generation sequencing data using multicommodity flows
BACKGROUND: Highly mutable RNA viruses exist in infected hosts as heterogeneous populations of genetically close variants known as quasispecies. Next-generation sequencing (NGS) allows for analysing a large number of viral sequences from infected patients, presenting a novel opportunity for studying...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698000/ https://www.ncbi.nlm.nih.gov/pubmed/23902469 http://dx.doi.org/10.1186/1471-2105-14-S9-S2 |